LL-37 – 10mg
LL-37 is a research peptide that has been studied for its potential role in antimicrobial activity, immune system signaling, and tissue repair mechanisms. For additional information, click here. This 10mg formulation is intended strictly for laboratory and scientific research purposes only. Not for human or veterinary use, consumption, or clinical application.
$100.00 / month
LL-37 is a synthetic peptide corresponding to the human cathelicidin antimicrobial peptide, supplied by Advanced Peptide Institute for laboratory research use only. Manufactured at 99% purity and third-party tested, this 10mg formulation is intended strictly for use by qualified researchers and laboratories investigating innate immune and host-defense peptide signaling.
What is LL-37?
LL-37 is derived from the C-terminal fragment of the human cathelicidin precursor protein hCAP18, placing it within the cathelicidin family of host-defense peptides that make up part of the innate immune system. Structurally, LL-37 is an amphipathic alpha-helical peptide, a conformation studied for its interaction with cell-membrane and receptor-level signaling. Published laboratory research has examined LL-37’s interaction with pattern-recognition and chemotactic signaling pathways, including receptor activity implicated in innate immune cell behavior, as well as its role in tissue-repair-associated signaling cascades. Advanced Peptide Institute’s LL-37 is synthesized to match this native peptide sequence and is supplied strictly for in vitro and non-human in vivo laboratory research.
Research Applications
LL-37 is commonly studied within innate immunology research, where scientists examine its interaction with host-defense signaling pathways and pattern-recognition receptor activity in cell-based and animal laboratory models. Researchers investigating chemotaxis frequently include LL-37 in assay panels exploring how host-defense peptides influence immune-cell recruitment and signaling cascades. LL-37 is also studied within tissue-repair signaling research, where laboratory models examine its interaction with pathways associated with cellular migration and extracellular-matrix signaling. Additional research contexts include membrane-biophysics studies of amphipathic peptide structure-function relationships, and laboratory investigations into receptor-binding kinetics and structure-activity relationships across the broader cathelicidin peptide family. All such research is conducted strictly in controlled laboratory settings using in vitro or non-human in vivo models.
Purity & Third-Party Testing
Every batch of Advanced Peptide Institute LL-37 is manufactured to 99% purity and independently verified through third-party High-Performance Liquid Chromatography (HPLC) testing and mass spectrometry analysis. This dual-verification process confirms both peptide identity and exact purity level prior to release for research use. A Certificate of Analysis (COA) documenting these results is available for every batch at https://advancedpeptideinstitute.com/certificate-of-analysis/, allowing researchers to confirm the exact specifications of the batch they receive before beginning any laboratory protocol.
Storage & Handling
Store lyophilized LL-37 at −20°C for long-term stability prior to reconstitution. Once reconstituted, refrigerate at 2–8°C and use within 4–6 weeks to preserve peptide integrity. Avoid repeated freeze-thaw cycles, protect the reconstituted solution from prolonged light exposure, and handle in accordance with standard laboratory safety protocols and institutional research-handling guidelines.
Frequently Asked Questions
What purity is Advanced Peptide Institute LL-37?
Advanced Peptide Institute LL-37 is supplied at 99% purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://advancedpeptideinstitute.com/certificate-of-analysis/.
How should LL-37 be stored?
Store lyophilised compound at −20°C for long-term stability. Refrigerate at 2–8°C after reconstitution and use within 4–6 weeks.
What is LL-37 studied for?
LL-37 is studied in laboratory research for its interaction with innate immune signaling and host-defense peptide pathways, strictly within research settings.
Published laboratory research on LL-37 is indexed on PubMed.
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For research use only. Not for human consumption. Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.